Background: 

Bitao has worked on Neuroscience research field for more than 20 years. He, as postdoctoral fellow, was trained in Laboratory of Neurophysiology at NIMH/NIH, MD and Department of Neuroscience at Georgetown University, Washington DC, USA between 1993 and 1997. Since 1997, he had had a research faculty position at Georgetown University until 2000. After then, he worked in industrial companies such as PG&E National Energy Group, Inc to develop software, computer applications and databases. He earned M.D., M.S. in Neurobiology and M.S. in Computer Science degrees, and is a Certified Java 2 and SAS programmer. He is interested in applying computer science and informatics knowledge to solve neuroscience research issues, that is, Neuroinformatics research. Currently he is working on web-accessed Synapse Databases and related analysis tools for Synapse Structure and Function Research.

Selected Publications:

Shi B and Harris K.M. (2004) Database of the Three-dimensional Ultrastructure of Neurons, Synapses and Glia. Human Brain Project Booth Presentation at the Society for Neuroscience Meeting.

Shi B and Harris K.M. (2004) Web-enabled database of synapse structure and function. Abstract #1032.4 Society for Neuroscience.

Mallei A, Shi B, Mocchetti I(2002) Antidepressant treatments induce the expression of basic fibroblast growth factor in cortical and hippocampal neurons. Mol Pharmacol. 2002 May;61(5):1017-24.

Brandoli C, Shi B, Pflug B, Andrews P, Wrathall JR, Mocchetti I(2001) Dexamethasone reduces the expression of p75 neurotrophin receptor and apoptosis in contused spinal cord. Brain Res Mol Brain Res. 2001 Feb 19;87(1):61-70

Shi B and Mocchetti I (2000) Dexamethasone induces TrkA and p75NTR immunoreactivity in the cerebral cortex and hippocampus, Exp Neurol/2000, 162:257-267

Shi B, Rabin S.J., Brandoli C and Mocchetti I. (1998) Dexamethasone induces hypertrophy of developing medial septum cholinergic neurons: potential role of nerve growth factor, J Neuroscience/1998, 18:9326-9334

Shi B and Stanfield B.B. (1996) Differential sprouting responses in axonal fiber systems in the dentate gyrus following lesions of the perforant path in Wlds mutant mice. Brain Res. 740/1-2, 89-101.

Zhang Z., Xu H., Wu Y. and Shi B (1993) Effects of homotopic and target transplantation of fetal cholinergic ventral basal forebrain graft on the rat model of Alzheimer’s disease. Chinese J. Neuroanatomy, 9(10), 11-16.

Shi B, Wu Y., Xu H. and Feng J. (1990) Study on the rat model of Alzheimer’s disease. Chinese J. Stereostactic and Functional Neurosurgery, 3(3), 36-40.

Shi B, Wu Y., Xu H. and Feng J. (1990) Effects of Embryonic ventral forebrain and cerebral cortex grafted into the neocortex of the rat model of Alzheimer’s disease. Chinese J. Stereostatic and Functional Neurosurgery, 3(4), 15-19.