Table of Contents
Short-term Synaptic Plasticity
Forms of Plasticity Distinguished By:
Forms of Plasticity Distinguished By:
Forms of Plasticity Distinguished By:
Sites and types of presynaptic Modifications
Sites and types of Postsynaptic Modifications
Short-Term Presynaptic Plasticity
(Regehr and Stevens, Chap. 3, Synapses)
Variable amplitude synaptic currents during spike trains
Reproducibility of responses
Key Questions
Consider the steps for modulation
Alterations in presynaptic axons
Changes in calcium entry during spike trains
Predictable changes in calcium influx patterns differ amongst synapses
Paired-Pulse Facilitation (PPF)
Presynaptic Calcium
Evidence that Cares may act at a higher affinity site than Caloc
Paired Pulse Depression (PPD)
More Cares speeds recovery from PPD
How multiple forms of plasticity interact to control synaptic strength during spike trains.
How multiple forms of plasticity interact to control synaptic strength during spike trains.
FD Model of Ca2+ dep. Short-Term Plasticity
Spike train responses are dependent on whether Facilitation or CDR are present
EPSCss during steady state relative to the First EPSC1
Short term Posttetanic Effects
Short term Posttetanic Effects
Short term Post tetanic Effects- Presynaptic
Short term Postsynaptic effects
Short term Postsynaptic effects
Short term Postsynaptic effects
|