Table of Contents
Modification of Brain Circuits as a Result of Experience
Process of Establishing Initial Brain Organization (Chapter 23, Dr. Li)
Role of Experience in the next stage of Neural Development
Experience Switching on Innate Behaviors
Plasticity in the Developing Brain
Critical Periods
Critical Periods
Critical Period for Language Acquisition (before 7 years)
Deaf Children with Signing Deaf Parents
Possible Roles of Experiencein Language Acquisition
Critical Periods and Vision
How studied?
Anatomical Projections
Axonal Transport of Radioactively Labeled amino acid such as proline
Normal Ocular Dominance Columns in Visual Cortex in Macque Monkey
Single Unit Responses in Normal Kitten Visual Cortex
Monocular deprivation in kitten
What about other parts of the Visual Pathway?
Longer monocular deprivation in the adult cat
Brief Monocular Deprivation During the Critical Period at 3-4 weeks postnatal
Ocular Dominance Columns have equal widths at Birth (Macaque Monkey)
Non-deprived eye captures more of Visual Cortex
Axonal branching expansion as basis of ocular dominance stripe widening
Activity dependent Competition
Neurons that Fire together Wire Together and their connections are preserved
Strabismis = uncorrelated activity
Other Brain Regions have similar developmental Critical periods
Summary
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