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Some types of synaptic specializations of dendrites.
(Adapted from Fiala and Harris, 1999.)
| Pattern | Characteristics | Examples |
|---|---|---|
Varicosity
| An enlargment in a thinner dendrite associated with synaptic contacts | Retinal amacrine cells |
Filopodium
| A long, thin protrusion with a dense actin matrix and few internal organelles | Normally only seen during development |
Simple Spine: Sessile
|
Synaptic protrusions without a neck constrictionStubby spine |
Pyramidal cells of cortex Cerebellar dentate nucleus |
Simple Spine: Pedunculated
|
Bulbous enlargement at tipThin spine |
Pyramidal cells of cortex Pyramidal cells of cortex Olfactory bulb granule cell |
Branched Spine
| Each branch has a unique presynaptic partner and each branch has the shape characteristics of a simple spine |
CA1 pyramidal cells Granule cells of dentate gyrus Cerebellar Purkinje cells |
Claw Ending
| Synaptic protrusions at the tip of the dendrite associated with one or more glomeruli | Granule cells of cerebellar cortex and dorsal cochlear nucleus |
Brush Ending
| Spray of complex dendritic protrusions at the end of dendrite that extends into glomerulus and contains presynaptic elements | Unipolar brush cells of cerebellar cortex and dorsal cochlear nucleus |
Thorny Excrescence
| Densely lobed dendritic protrusion into a glomerulus | Proximal dendrites of CA3 pyramidal cells and dentate gyrus mossy cells |
Racemose Appendage
| Twig-like branched dendritic appendages that contain synaptic varicosities and bulbous tips |
Inferior olive Relay cells of lateral geniculate nucleus |
Coralline Excrescence
| Dendritic varicosity extending numerous thin protrusions, velamentous expansions and tendrils |
Cerebellar dentate nucleus Lateral vestibular nucleus |
| Last Updated: 11/4/99 |